average daily cigarette consumption Number of smokers Adult cigarette smoking rate overall

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The brands below are just two of the many 'safer' cigarette prototypes

To help minimize the influence of outliers, average or mean expression across cells was always calculated as the geometric mean, where a fixed value of 1 was added to each normalized count to avoid taking the log of zero

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The main weakness was that the study centers had not previously been involved in smoking cessation programs or worked with either pharmaceutical or behavioral cessation interventions