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In his later life, Dangerfield suffered wild mood swings and sometimes stayed in bed all day under the covers, refusing to come out

Incisional biopsy: A portion of the abnormal tissue is removed for examination

For example, moving from unfiltered to filtered cigarettes, and from regular to "low tar" cigarettes, both appear to reduce the risk of lung cancer

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"But contrary to Big Tobacco's belief that banning displays would make no difference this study shows that by putting cigarettes out of sight and out of mind far fewer youngsters are taking up the deathly habit." Duncan Selbie, chief executive of Public Health England, said: "Banning the display of tobacco products at point-of-sale has worked and it's fabulous that more young people are now turning their backs on smoking, literally saving thousands of lives." The Scottish government said it had invested 10m annually over the last five years in stop-smoking services