MD Ashok Nayak highlighted: Despite our plant remaining affected due to the fire impact for the larger part of the year, we are happy to share that we have grown 5% year-over-year, thanks to the teams resilience and strong fundamentals of our API business. The companys API portfolio centers on immunosuppressants (Azathioprine) and niche generics (Haloperidol, Risperidone, Nicorandil) more specialty in character than commodity
November 2025
The SURMOUNT-5 head-to-head comparison trial provided definitive evidence of tirzepatide's superiority over semaglutide, with Zepbound producing 20.2% average weight loss compared to 13.7% for Wegovy, a 47% greater relative reduction
Weeks 9 through 12: 4 mg weekly
Insulin gene expression is upregulated in pancreatic -cells after GLP-1R activation, which increases insulin mRNA expression through activation of transcription factors such as pancreatic and duodenal homeobox-1 and cAMP-response element binding protein (Table 1), contributing to an increase in -cell numbers (Liu et al., 2024)
How They Work: Central and Peripheral Effects The effects of GLP-1 receptor agonists operate on two levels simultaneously, and understanding both is important for appreciating why they are relevant to the menopausal metabolic transition described in the previous section
