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In addition, smoking is a major contributor to cardiovascular diseases such as ischaemic heart disease, stroke and other artery-related diseases, including microarterial and capillary diseases

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Antihistamines Certain OTC antihistamine drugs (e.g., diphenhydramine, chlorpheniramine, and hydroxyzine) may increase the risk of topiramate side effects such as dizziness, sleepiness, or trouble concentrating