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Treatment Goals Aggressive goals may require higher doses or longer treatment duration

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However, it has been recently described that mTORC2 also possesses tyrosine phosphorylation capacity [118], and that it phosphorylates tyrosines on IRS and tyrosine kinases in both receptors, IGF-1 and IR, thus reinstituting the signal of the activated receptors [118]

References to biological effects are limited to research context only and must not be interpreted as claims of therapeutic, diagnostic, or clinical benefit

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