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Mitochondrial Function

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The advantages of functionalized lipid nanoparticles encompass enhanced penetration and an extended residence time of therapeutic molecules at the blood-brain barrier (156158)

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The gRNA typically consists of a scaffold region required for Cas protein interaction and a ~ 20-nucleotide spacer sequence complementary to the target DNA region, thereby directing sequence-specific cleavage at the desired genomic locus [47, 143]