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More than 20,000 deaths each year in Ohio can be directly attributable to smoking

"Selling luxury: The rise of the Egyptian cigarette and the transformation of the Egyptian tobacco market, 18501914." International Journal of Middle East Studies 35.1 (2003): 51-75

Nat Biotechnol 26:11351145

Nicotine was the substance most strongly associated with sleep disruption

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A meta-analysis of 23 population-based studies including a total of 141,317 individuals also found that there was no causal association between smoking heaviness in current smokers and SBP or DBP [26]