Insight into the mechanisms regulating immune homeostasis in health and disease
Nevertheless, the interaction between LC3, SQSTM1, and Keap1 still remains controversial, as the binding competition to SQSTM1 between Keap1 and LC3 can be attributed to the spatial adjacency of the LIR domain and KIR domain in SQSTM1 (Jain et al., 2010)
2021;34:e4266
Studies have also found a close relationship between NapA, SodB, and ferritin, which plays a role in storing Fe 3+ and preventing its availability to promote ferroptosis [42]
Combining a systemic bone-building signal with a compound that may enhance local blood supply and cellular recruitment at the fracture site is a compelling research avenue
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