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doi: 10.1016/j.neuint.2016.12.005

However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]

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It included a total of 91,408 patients

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Because gastric emptying is delayed, eating too quickly can lead to a rapid build-up of food in the stomach before fullness signals are registered, resulting in nausea or discomfort