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Billings, 247 (second quotation)

In general, these results show that e-cigarette use could trigger arrhythmias by inducing autonomic imbalance, and the magnitude and characteristics of the reaction may depend on chemicals in the e-liquids, such as nicotine, solvents, and flavors

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Federal Trade Commission

Bladder cancer risk increases with smoking duration (the number of years you have smoked) and intensity (the number of cigarettes smoked each day), although duration appears to have a greater effect