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Cancer Lett 17:125134 Stratton KS, Shetty P, Wallace R, Bondurant S (eds) (2001) Clearing the smoke: assessing the science base for tobacco harm reduction

These are things that make you think about chewing tobacco - and can lead to cravings

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Causes of nicotine addiction include effects on neurotransmitters, availability of nicotine-containing items, psychological factors, social and environmental influences, and genetic factors