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30 demonstrated that smoking-induced hypomethylation in AHRR and F2RL3 contributes to the risk of lung cancer, providing evidence of specific altered methylation that can mediate the effect of smoking on cancer pathogenesis

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Evaluation of Statewide Restrictions on Flavored E-Cigarette Sales in the US From 2014-2020, JAMA Network E-cigarette sales data from 4 states that imposed sales restrictions on the sale of flavored e-cigarettes and 35 states that did impose sales restrictions shows that the restrictions were associated with a decrease in total e-cigarettes sales, meaning that not all people who were using flavored e-cigarettes switched to tobacco flavor when the restrictions were imposed, but instead likely quit using e-cigarettes