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And thats a good thing, Jones says

They are far less likely to stain your teeth compared to smoking or chewing tobacco

It is associated with decreased fertility in both males and females and can have a significant negative impact on the clinical outcome of assisted reproduction treatment (ART)

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In the large postmarketing neuropsychiatric safety outcome trial, an analysis of adjudicated MACE events was conducted for patients while in the trial and during a 28-week non-treatment extension period