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Integrative analyses showed associations between microbial composition and host gene expression, such as CD74 positively correlated with Lactobacillus and PPP1R3C negatively with Bacteroidota, suggesting that smoking-induced microbial shifted might interact with host transcriptional programs to promote OSCC progression [59]

Additionally, smoking is strongly linked to several cancers, including those of the oral cavity, upper digestive tract, lung, bladder, kidney, and liver

While nicotine may support symptom management, it isnt a root-cause solution

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