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Golgi staining of aged astrocytes did not show major morphological changes 529 , whereas age-dependent changes in astrocytes stained with antibodies against S100B and glutamine synthetase are characterised by complex region-dependent changes ranging from atrophy to hypertrophy

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There was also no significant difference found in the secondary outcome of general distribution of specific hangover symptoms including headache with NAC and Placebo both with median = 1 ( P = 0.93), nausea with median score for NAC = 0, and Placebo = 1 ( P = 0.11), and weakness with NAC median = 1, and Placebo median = 1 ( P = 0.72)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 274.Litchfield J.T., Jr