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Gene ontology (GO) analysis of upregulated DEGs in SCyte_lP cells demonstrated significant enrichment in respiratory chain complexes, especially complex IV, including key genes such as mt-Co1 , mt-Co2 , Cox5a , and Cox6c (Fig

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Bupropion acts as an inhibitor in the CYP2D6 pathway, a common metabolic pathway for many antidepressant and antipsychotic medicines including venlafaxine and tricyclic antidepressants

The metabolism of p -OHA to p -OHNor is well documented and dopamine- hydroxylase present in noradrenergic neurons could easily convert p -OHA to p -OHNor after intraventricular administration

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