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Long-term effects of cigarette-smoke exposure on plasma testosterone, luteinizing hormone and follicle-stimulating hormone levels in male rats

A 2013 study 38 Minichino, A., Bersani, F

Initially (pre-21st century), cigarettes were used for their "medicinal properties." However, mounting research and evidence show that these properties were often a byproduct of their addictive properties and placebo effects

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Nicotine in diseases Smoking inserts a high amount of xenobiotics, which in turn can alkylate DNA, activate specific (anti)inflammatory signals, and oxidative stress in active smokers and also second-hand smokers [167, 168]

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