doi: 10.1007/s00204-009-0487-y 18 MaiorinoMConradMUrsiniF
Second, many clinical trials are of relatively short duration (often 6 months), failing to capture the long-term efficacy and sustainability of interventions on OA progression, a inherently chronic disease
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As a potent mitochondrial redox regulator, CoQ10 could prevent thrombotic events in COVID-19 and PASC patients by resolving ROS-induced platelet aggregation 539
Furthermore, blocking the recruitment of peripheral effector T cells could significantly reduce neuronal damage and improve clinical prognostic indicators in different cerebral ischemias ( Figure 3 ) (76, 96)
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