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When users inhale or otherwise use nicotine-containing products, the addictive drug makes its way quickly to the brain where it drives the release of dopamine, a chemical that signals pleasure and keeps users addicted to nicotine

Reducing Vaping Among Youth and Young Adults An Evidence-Based Resource Guide published by SAMHSA

When you smoke, nicotine causes the opposite effect: it raises blood pressure, constricts arteries, and thickens blood

There have been a number of publications on this form of misclassification

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Although it states that it uses an Interfacing check and gives the player odds of success, the player will always fail this check even if a natural 12 is rolled regardless of the character's Interfacing skill