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Tangs team had shown in a February 2018 PNAS article that e-cigarette smoke induces DNA damage in the mouse lung and bladder, and that nitrosation in cultured human lung and bladder cells converts nicotine into derivatives that increase DNA code changes, or mutations, with the potential to transform normal cells into cancer cells

These triggers include acquaintances who smoke, smoking environments, and activities that have come to be associated with lighting a cigarette, such as having coffee or drinking alcohol

Among participants whose parents did not currently smoke, children's smoking attitudes were associated with a 1.7 times increased risk for ever smoking, whereas among participants who reported that at least one parent currently smoked, children's smoking attitudes were associated with a 2.5 times increased risk

Cataracts could also be inherited or caused by an underlying medical condition