It is a naturally occurring peptide that is heavily involved in cell proliferation, migration, and specialization
Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits
The B12 does not need to be converted by your genes/enzymes in order to be available for use
Adipose-selective fat metabolism
Safety Profile: What Clinical Trials Actually Documented Across six clinical trials involving approximately 900 participants, AOD-9604 produced no treatment-related serious adverse events, no immunogenic response, no IGF-1 elevation, and no adverse cardiovascular or metabolic signals
All 12 had already tried the only FDA-approved drug for it and it did not work