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32 Higher levels of malondialdehyde observed in the experimental subjects compared to healthy controls and nitric oxide as oxidative stress marker are due to the chronic exposure to smokeless tobacco which results in the greatest amount of reactive oxygen species production in cells and tissues

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The American Dental Associations MouthHealthy notes that smoking a cigarette typically takes five to seventy-five minutes, with forty to seventy-five puffs

Health effects associated with smokeless tobacco

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