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SR18 exhibited an average hydrodynamic diameter of 4.001 nm with a polydispersity index (PDI) of 0.2289, indicating a relatively uniform and predominantly monomeric population in 1 X PBS, compared to 10 M BSA (hydrodynamic diameter 7.631 nm and PDI 0.1645) as shown in Supplementary Figure S5

Amycretin is a single peptide engineered to activate both receptors simultaneously and has demonstrated up to 24% weight loss in Phase 2 trials, essentially on par with current medications

The SmPC does not list specific antibiotic interactions or routine dose adjustments

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The self-assembled nature of these nanoparticles not only addresses the instability issues of GHK-Cu in biological fluids but also enhances their antibacterial efficacy