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These findings are consistent with our multiomic analyses displaying the upregulation of PPARA in BWS patient hepatocytes and further validate our iPSC model as properly recapitulating BWS phenotypes

Linked with metabolic regulation and nutrient processing

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For simultaneous GSH and GSSG measurement: HPLC-MS/MS or HPLC with fluorescence detection offers the specificity needed to resolve both species in a single run

Furthermore, L-carnitine improves insulin sensitivity, which is common in Type 2 diabetes patients

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