Vitamin B12 is an essential water-soluble nutrient, also known as cobalamin
Its available as a research peptide or for investigational purposes under physician supervision
History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy
Methylcobalamin is a naturally occurring form that may offer added benefits for those with severe deficiencies or neurological symptoms
"Vitamin B12 deficiency and use of proton pump inhibitors: a systematic review and meta-analysis"
By enhancing mitochondrial capacity and SIRT1 signaling, 5-Amino-1MQ restores metabolic flexibility