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On January 16, 2025, the FDA announced the authorization of 20 flavored Zyn products, including Zyn Chill and Zyn Smooth

Available from: www.rctfi.org/, accessed on May 2, 2013 International Agency for Research on Cancer

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We have maintained a data completeness criteria threshold of at least 70 percent for 4 years from the CY 2020 performance period through the CY 2023 performance period and as a result, individual MIPS eligible clinicians, groups, virtual groups, and APM Entities had 4 years of a maintained data completeness criteria threshold of at least 70 percent before transitioning to an increased data completeness criteria threshold of at least 75 percent starting with the CY 2024 performance period

To this end, there has been an increasing shift from using the gold standard endpoint of overall survival (OS) (see Sidebar 28 ), to earlier endpoints like progression free survival, overall response rate, and duration of response to achieve an accelerated approval designation from FDA

The evidence is that's very effective, but it's diminishing in its effect