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High circulating levels of TMAO have been identified as a biomarker associated with an increased risk of cardiovascular disease and systemic inflammation

Federal Trade Commission (FTC) charged a chelation-advocacy group, the "American College for Advancement in Medicine" (ACAM), with making false or unsubstantiated claims when they promoted chelation therapy for heart disease on their website and on a brochure they published

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The result is reported in EU/mg on the Certificate of Analysis at cell-culture-reference acceptance limits, allowing the material to be used in sterile adipocyte and chondrocyte assays without LPS-driven confounding signals