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These doses are approximately 2, 4, and 8 times in males, and 3, 7, 12, and 16 times in females of the maximum recommended human daily dose of 2000 mg based on body surface area comparisons

These improvements correlate with weight loss but appear partly independent of it, suggesting direct metabolic benefits

The evidence does not support using tirzepatide as a treatment for autoimmune disease

The blend is co-lyophilized as a single cake, so the four peptides cannot be physically separated post-formulation