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In this study, our results suggested that the core targets among riboflavin, osteogenesis and osteoclastogenesis included HIF1A, HDAC2/3/4, TP53, PPARG, PPARGC1A, NFKB1, MYC and BCL2, and the potential signaling pathways of vitamin B2 involved in regulating bone health focused on HIF-1 signaling pathway, p53 signaling pathway, AGE-RAGE signaling pathway, longevity regulating pathway, and so on

PMID: 39263264

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Bielinski SJ, Yanes Cardozo LL, Takahashi PY, Larson NB, Castillo A, Podwika A, De Filippis E, Hernandez V, Mahajan GJ, Gonzalez C, Shubhangi, Decker PA, Killian JM, Olson JE, St Sauver JL, Shah P, Vella A, Ryu E, Liu H, Marshall GD, Cerhan JR, Singh D, Summers RL

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