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PI3K/mTOR inhibition attenuates cigarette smoke-induced senescence and SASP in oral fibroblasts: implications for tumor microenvironment remodeling Nicla Flacco, Cristina Estornut, Ins Roger, Pilar Ribera, Germn Snchez-Herrera, Silvia Trujillo-Barbera, Martn Prez-Leal Frontiers in Cell and Developmental Biology 30

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And, of course, theres the ever-present reminder of the dangers of smoking, which can make the idea of bringing cigarettes across the border feel a bit guilt-inducing