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Pauls Hospital endocrinologist and member of the Physicians for a Smoke-Free Canada, said in an email

A perforated septum does affect on the voice: Nasal resonance: the voice sounds more nasal Post nasal drip: increased nasal secretions due to a septal perforation will drip onto the vocal cords, cause mild hoarseness and throat clearing It will not cause a loss of vocal range nor should it produce chronic raspiness

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