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coli ) Per FDA, should only be used when benefits outweigh potential risks if treating acute sinusitis, acute bronchitis or uncomplicated urinary tract infections FDA boxed warnings: tendonitis, tendon rupture, CNS effects, peripheral neuropathy, can worsen existing myasthenia gravis FDA warnings: hypoglycemia (including coma), altered mental health, aortic dissection Other ADRs to beware: QTC prolongation, photosensitivitity Suicidal thoughts added to drug safety label warning by the FDA in February 2017 RESOURCES Oral Ciprofloxacin Package Insert IV Ciprofloxacin Package Insert IDSA Practice Guidelines CDC Sexually Transmitted Diseases Guidelines (2015) Guidelines From AIDSinfo.NIH.gov Mayo Clinic Proceedings Fluoroquinolone Review 1999 Collateral Dammage Fluoroquinolones Fluoroquinolone Black Boxed Warnings Viewpoint (2016)

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