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This finding bolsters support for including smoking cessation as part of addiction treatment. Although cigarette smoking is on the decline, smoking continues to be the leading preventable cause of morbidity and mortality in the U.S

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5-HT 1A binding was negatively correlated with age in BA9, BA46 and BA32 (Pearson correlation values 0.141, 0.147, 0.151, p values 0.037, 0.037 and 0.029 respectively)