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In this paper, while we report that the nicotine concentration in the aerosol from both conventional and electronic waterpipe was approximately 2- to 4-times higher than that in 3R4F reference cigarette smoke when assessed on a per session or per stick basis, it has to be considered that waterpipe use sessions last much longer than cigarette smoking sessions and include substantially more puffs 42

Our findings shed new light on how the microbiome interacts with the human gut in ways that may be therapeutically exploited" The second bioactive metabolite, acetylglycine, or ACG, followed a mirror-image pattern to that of DMG: Its levels were reduced during active exposure to smoke and after the exposure stopped, they increased following antibiotic treatment

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