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[4] Most ZYN users consume 8-12 pouches per day, but the amount is totally up to you

Although nicotine is crucial in increasing cardiac output, pulse rate, and blood pressure, its role in athero-thrombotic diseases is poorly understood ( 14 )

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Furthermore, the results argue that nicotine, once inside cells, is converted into nitrosamines that do not leave cells and, therefore, could never be captured by tests that measure nitrosamine levels outside of cells, for example blood tests, says Dr