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Methods Participants The dataset used for the present study was selected from the IMAGEN project, which was a prospective, multicentre longitudinal imaging genetics study that recruited 2000 healthy adolescents

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Moreover, studies utilising a cross-sectional design analyse a single point in time or pooled data, and they do not consider potential changes in mental health outcomes [6, 16, 44], commonly due to a lack of available high-quality longitudinal or life course data

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