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Denoting the rsfMRI data of one voxel by x = [ x 1 , x 2 , , x N ], where N is the number of acquisitions, SampEn calculation starts with forming a series of vector sequences, each with m consecutive points extracted from x : u i = [ x i , x i +1, , x i + m 1], where i = 1( N m + 1), and m is the pre-defined window size (3, as stated above)

In some cases, individuals may also experience facial pain or discomfort that can extend to the neck and shoulders, further complicating the diagnosis and treatment