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As a key methyltransferase of m6A, METTL3 can inhibit the activation of pTHP-1 macrophages by preventing the generation of IL-6 and TNF-, and attenuate inflammatory response induced by LPS via the NF-B signaling pathway (178)

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Antimicrobial peptides calm infection-driven inflammation not only by killing microbes, but by sending signals to immune cells to cool it

Even when blood sugar is technically within normal range, cellular energy production can be compromised