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Choroid plexus acts as gatekeeper for TREM2, abnormal accumulation of ApoE, and fibrillary tau in Alzheimers disease and in Down syndrome dementia

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However, contact your GP if altered appetite prevents you from maintaining adequate nutrition or significantly affects your quality of life, as dose adjustments or dietary support may be needed

[234] Alcohol consumption should be discussed with your healthcare provider, as it may potentially enhance certain side effects

Reddit is also full of threads with people on GLP-1s discussing how they feel weak as a result of muscle loss

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