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Acquired PGA elevation can also occur during chronic acetaminophen use [67, 68] as acetaminophen metabolism consumes glutathione through conjugation reactions, thereby depleting GSH stores and increasing metabolic flux toward PGA formation [69]

Furthermore, Figure 4D confirmed that H 2 O 2 increased the content of cellular ROS, while both targeting peptides obviously reduced the fluorescence intensity of the cellular ROS probe compared to that of GHK, especially RGD-GHK inhibited approximately 40% of ROS production

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Total gastrectomy always produces vitamin B12 deficiency

A no-template control reaction was included for each gene examined

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