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In a statement, Juul says it "will continue to develop scientific evidence to support the use of these flavored products." Oct

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Changes in the redox status within the cell initiate the lung inflammatory responses through enhancement of the respiratory burst in phagocytic cells, regulation of intracellular signalling, chromatin remodeling (histone acetylation/deacetylation) and activation of redox-sensitive transcription factors, such as nuclear factor-B (NF-B) and activator protein-1 (AP-1)

2 This article was authored by students Justina John and Kai Snodgrass , and Verity Ramirez, MD, FACC , Warren Alpert Medical School, Brown University, Providence, RI, and a member of ACC's Prevention of Cardiovascular Disease Section