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This paradoxical improvement occurs because pain reduction outweighs any stimulatory effect on neurotransmitters

In G6PD-deficient individuals, epithelial and mesenchymal cells such as fibroblasts and lenses, exhibit decreased enzyme activity (102, 103)

[DOI] [PMC free article] [PubMed] [Google Scholar] 160.Biolo G., Stulle M., Bianco F., Mengozzi G., Barazzoni R., Vasile A., Panzetta G., Guarnieri G

Therefore, the findings summarized in this review should be interpreted with caution, considering the potential influence of publication bias and reporting variability

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Reduction of GBB with L-CN may lead to impaired conversion of L-CN to acylcarnitines 42 , which have been shown to be anticoagulants inhibiting factor Xa by metabolomics in VTE 10