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By inhaling its smoke, the nicotine within tobacco binds with the brains nicotinic cholinergic receptors, thereby releasing acetylcholine

Nandakumar A, Thimmasetty KT, Sreeramareddy NM, Venugopal TC, Rajanna, Vinutha AT, et al

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It provides rapid relief from cravings and can be used as needed throughout the day