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Statistical analysis Non-paired t-test, one-way ANOVA, two-way ANOVA, and linear regression analysis were performed with GraphPad Prism 7 (GraphPad, San Diego, CA)

As collagen production naturally decreases with age, many patients seek therapies that support healthy collagen levels

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the same study showed increased vessel density in vitro and in vivo and faster blood-flow recovery in a rat hind-limb ischemia model

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