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The Impact of Nicotine on Mood Nicotine acts as a stimulant, leading to an initial increase in mood and alertness

6 Pulmonary function and physical activity in adolescents: influence of e-cigarette use 6.1 Adolescent pulmonary function and exercise capacity Adolescence is a critical period for lung development, during which pulmonary function metrics like forced expiratory volume in one second (FEV) and forced vital capacity (FVC) increase rapidly and reach their peak in early adulthood (67)

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One shortcoming of the study is that more than half of the patients in each treatment group stopped therapy before the 12-week regimen was completed, the authors note