"The genome of every cancer provides a kind of 'archaeological record', written in the DNA code itself, of the exposures that caused the mutations that lead to the cancer," explained joint lead author Sir Mike Stratton from the Wellcome Trust Sanger Institute
Awareness in Italy about the dangers of smoking has evolved significantly since the end of World War II when smoking seemed to pervade all Italian spaces, or perhaps since 1962 when Vittorio Gassman in the delightful Il sorpasso ( The Easy Life ) warned the till then sheltered Jean-Louis Tritignant that NOT smoking was bad for his health
"2005, 11th Annual Awards, March 20, 2005"
Spontaneous rupture of large arteries was not observed at all and, in particular, neither in the 6 patients with the COL1A1 p.(Arg312Cys) missense variant nor in 2 individuals with different COL5A1 glycine substitutions at the C-terminal domain (Additional Table 1), which represent variants previously associated with a possible higher risk of vascular events [16]
PMID 16020846
Filters or Tips: Filters, also known as tips, are optional but can enhance the smoking experience