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Patients were randomized to TRESIBA once-daily with the evening meal or insulin glargine U-100 once-daily according to the approved labeling

Its also consistently with in vitro experiment that the gene expression of CPT1B was upregulated in HUA model group compare with the blank group, but the differences showed no significance (Figure 5D)

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While GLP-1 medications have shown remarkable results for weight loss, they may also lead to some muscle loss