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For HFA inhalers, adults typically use 1 to 2 puffs every 4 to 6 hours as needed

CRP binds and aggregates oxidized low-density lipoprotein (ox-LDL) and enhances macrophage oxLDL uptake, promoting mitogen-activated protein kinase activation (171) required for foam cell formation (172)

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doi: 10.1073/pnas.1716095115 83 MatarreseP.FalzanoL.FabbriA.GambardellaL.FrankC.GenyB.et al