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Irrespective of etiology and scar type (surgical, burn, axillary webbing, frozen shoulder, or repeat strain), fibrosis constitutes the characteristic physical attribute of abnormal (pathological) tissue remodeling in response to insult

Our structure identified an unpredicted non-peptide agonist-binding pocket in which reorganization of extracellular loop 3 and transmembrane helices 6 and 7 manifests independently of direct ligand interaction within the deep transmembrane domain pocket

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Glucagon-like peptide-1 receptor in the human hypothalamus is associated with body mass index and colocalizes with the anorexigenic neuropeptide nucleobindin-2/nesfatin-1

Mantovani G, Maccio A, Madeddu C, Serpe R, Massa E, Dessi M, Panzone F, Contu P