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Further studies indicate that NEDD4L may restrain IPF progression by promoting -catenin ubiquitination, thereby inhibiting Wnt/-catenin signaling and suppressing the CTHRC1/HIF-1 axis, which diminishes the activity and differentiation of lung fibroblasts (LFs)
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Our results suggest no significant temporal effect of menthol on the esophageal motility or LES function, neither in healthy volunteers, nor in GERD
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